Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 57817
Gene Symbol: HAMP
HAMP
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD  Differences in hepatic expression of iron, inflammation and stress-related genes in patients with nonalcoholic steatohepatitis. 28051796

2017

Entrez Id: 4023
Gene Symbol: LPL
LPL
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD [Preventive and therapeutic effects of compound ginkgo extract in rats with nonalcoholic steatohepatitis induced by high-fat, high-fructose diet]. 27978932

2016

Entrez Id: 3606
Gene Symbol: IL18
IL18
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD [Influence of electroacupuncture stimulation on serum and hepatic interleukin-18 expression in nonalcoholic fatty liver rats]. 24006666

2013

Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD [Effects of telmisartan on nonalcoholic steatohepatitis rat model by activating peroxisome proliferator-activated receptor r]. 22152320

2011

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD [Effects of puerarin on expressions of leptin receptor mRNA, phosphorylated Janus kinase 2/phosphorylated signal transducers and activators of transcription 3 proteins in the liver of rats with non-alcoholic fatty liver]. 18782535

2008

Entrez Id: 3717
Gene Symbol: JAK2
JAK2
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD [Effects of puerarin on expressions of leptin receptor mRNA, phosphorylated Janus kinase 2/phosphorylated signal transducers and activators of transcription 3 proteins in the liver of rats with non-alcoholic fatty liver]. 18782535

2008

Entrez Id: 3643
Gene Symbol: INSR
INSR
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD [Effects of Lactobacillus paracasei N1115 combined with fructooligosaccharides on non-alcoholic fatty liver disease induced by high-fat diet in mice]. 29325294

2017

Entrez Id: 7124
Gene Symbol: TNF
TNF
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD [Effect of electroacupuncture stimulation of back-shu points on expression of TNF-alpha and lipid peroxidation reaction in the liver tissue in non-alcoholic fatty liver disease rats]. 25219124

2014

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD [Effect of electro-acupuncture on hepatic Toll-like receptor 4 and nuclear factor κB expressions in rats with non-alcoholic fatty liver disease]. 25413054

2014

Entrez Id: 1728
Gene Symbol: NQO1
NQO1
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Yinchen Linggui Zhugan Decoction Ameliorates Nonalcoholic Fatty Liver Disease in Rats by Regulating the Nrf2/ARE Signaling Pathway. 28932253

2017

Entrez Id: 4023
Gene Symbol: LPL
LPL
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Thiazolidinedione induces a therapeutic effect on hepatosteatosis by regulating stearoyl-CoA desaturase-1, lipase activity, leptin and resistin. 30214514

2018

Entrez Id: 37
Gene Symbol: ACADVL
ACADVL
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD The modulation of hepatic adenosine triphosphate and inflammation by eicosapentaenoic acid during severe fibrotic progression in the SHRSP5/Dmcr rat model. 22569299

2012

Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD The expression of SIRT1 in nonalcoholic fatty liver disease induced by high-fat diet in rats. 17498258

2007

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593

2017

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 ModifyingMutation RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593

2017

Entrez Id: 34
Gene Symbol: ACADM
ACADM
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Selenium significantly inhibits adipocyte hypertrophy and abdominal fat accumulation in OLETF rats via induction of fatty acid β-oxidation. 23076603

2012

Entrez Id: 37
Gene Symbol: ACADVL
ACADVL
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Selenium significantly inhibits adipocyte hypertrophy and abdominal fat accumulation in OLETF rats via induction of fatty acid β-oxidation. 23076603

2012

Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Role of AMP-activated protein kinase and adiponectin during development of hepatic steatosis in high-fat diet-induced obesity in rats. 21255792

2011

Entrez Id: 3667
Gene Symbol: IRS1
IRS1
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Regulation of synthesis and oxidation of fatty acids by adiponectin receptors (AdipoR1/R2) and insulin receptor substrate isoforms (IRS-1/-2) of the liver in a nonalcoholic steatohepatitis animal model. 20846698

2011

Entrez Id: 8660
Gene Symbol: IRS2
IRS2
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Regulation of synthesis and oxidation of fatty acids by adiponectin receptors (AdipoR1/R2) and insulin receptor substrate isoforms (IRS-1/-2) of the liver in a nonalcoholic steatohepatitis animal model. 20846698

2011

Entrez Id: 3030
Gene Symbol: HADHA
HADHA
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Proteomic analysis of liver mitochondria from rats with nonalcoholic steatohepatitis. 24782632

2014

Entrez Id: 60
Gene Symbol: ACTB
ACTB
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Protein carbonylation associated to high-fat, high-sucrose diet and its metabolic effects. 25282656

2014

Entrez Id: 3479
Gene Symbol: IGF1
IGF1
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 SusceptibilityMutation RGD Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats. 24275070

2014

Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 SusceptibilityMutation RGD Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats. 24275070

2014

Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Pioglitazone, quercetin and hydroxy citric acid effect on cytochrome P450 2E1 (CYP2E1) enzyme levels in experimentally induced non alcoholic steatohepatitis (NASH). 25317811

2014